

HY-107508 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-107508
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medchemexpress.com/vu-29.htmlDescription
VU-29 is a positive allosteric modulator of metabotropic glutamate 5 mGlu5 receptor EC50=9 nM and Ki=244 nM for rmGluR5 . VU-29 is selective for mGluR5 relative to other mGluR subtypes EC50: rmGluR1/rmGluR2=557 nM/1.5 ?M; hmGluR4=154 nM .