

HY-19752A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19752A
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medchemexpress.com/VU0357017-hydrochloride.htmlDescription
VU0357017 hydrochloride CID-25010775 is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested 30 ?M . VU0357017 hydrochloride can be used for the research of AlzheimerAAasAasAas disease and schizophrenia.