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VU0357017 hydrochloride
GENERAL CATALOGUE

VU0357017 hydrochloride

HY-19752A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-19752A

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Catalog No: HY-19752A
CAS No: 1135242-13-5
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

VU0357017 hydrochloride CID-25010775 is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested 30 ?M . VU0357017 hydrochloride can be used for the research of AlzheimerAAasAasAas disease and schizophrenia.

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