GENERAL CATALOGUE
VU0360172 hydrochloride
HY-107504 · 5 mg
MedChemExpress · Cat: HY-107504
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medchemexpress.com/vu0360172-hydrochloride.htmlCatalog No: HY-107504
CAS No: 1309976-62-2
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
VU0360172 hydrochloride is a potent and selective mGlu5 receptor positive allosteric modulator PAM with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 hydrochloride stimulates polyphosphoinositide PI hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice.
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