GENERAL CATALOGUE
VU10010
HY-14563 · 5 mg
MedChemExpress · Cat: HY-14563
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medchemexpress.com/vu10010.htmlCatalog No: HY-14563
CAS No: 633283-39-3
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
VU10010 is a potent, highly selective and allosteric M4 mAChR potentiator with an EC50 of 400 nM. VU10010 binds to an allosteric site on M4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus.
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