GENERAL CATALOGUE
VU6024578
HY-170499 · 50 mg
MedChemExpress · Cat: HY-170499
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Manufacturer product page
medchemexpress.com/vu6024578.htmlCatalog No: HY-170499
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
VU6024578 BI02982816 is a selective, orally active positive allosteric modulator PAM for metabotropic glutamate receptor mGluR1 , that activates human mGluR1 and rat mGluR1 with EC50 of 54 nM and 46 nM. VU6024578 exhibits antipsychotic activity in rats amphetamine-induced hyperactivity models and MK-801 HY-15084B -induced novel object recognition NOR models. VU6024578 is blood brain barrier penetrable.
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