GENERAL CATALOGUE
VUF10166
HY-100552 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100552
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Catalog No: HY-100552
CAS No: 155584-74-0
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
VUF10166 is a potent and high-affinity 5-HT3 receptor antagonist, with Ki values of 0.04 nM 5-HT3A and 22 nM 5-HT3AB . VUF10166 inhibits 5-HT-induced responses at 5-HT3A and 5-HT3AB receptors at nanomolar concentrations. At 5-HT3 receptor, VUF10166 at higher concentrations also acts as a partial agonist, with an EC50 of 5.2 ?M.
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