GENERAL CATALOGUE
VX5
HY-P991567 · 1 mg
MedChemExpress · Cat: HY-P991567
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medchemexpress.com/vx5.html
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Catalog No: HY-P991567
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
VX5 is a humanized IgG1? monoclonal antibody inhibitor targeting BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration EC50s for 105 and 253 nM for human tonsillar and pre-B-697-hCXCR5 cells, respectively . VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer.
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