GENERAL CATALOGUE
W4275
HY-168035 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-168035
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Catalog No: HY-168035
CAS No: 3051650-00-8
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
W4275 Compound 42 is a selective NSD2 inhibitor with oral activity, showing an IC50 value of 17 nM. W4275 exhibits antiproliferative activity with an IC50 of 230 nM against RS411 cells and significantly inhibits tumor growth in the RS411 tumor xenograft model. Pharmacokinetic analysis in mice demonstrates that W4275 has good oral bioavailability F of 27.34 % . W4275 holds promise for use in cancer research.
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