WAY 163909 hydrochloride

Description

WAY-163909 hydrochloride is a potent 5-hydroxytryptamine receptor 2C 5-HT2C agonist with an EC50 of 8 nM and a maximum efficacy of 90 %, while displaying minimal activity at 5-HT2A receptors. Its selectivity is further demonstrated by Ki values of 10.5 nM for 5-HT2C, alongside higher Ki values for 5-HT2A 212 nM , 5-HT7 343 nM , and 5-HT2B 485 nM , and it lacks significant activity at various other receptors.