

HY-133121 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-133121
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medchemexpress.com/wdr5-in-1.htmlDescription
WDR5-IN-1 is a potent and selective WD repeat domain 5 WDR5 inhibitor, with a Kd of 0.02 nM. WDR5-IN-1 inhibits MLL1 histone methyltransferase HMT activity with an IC50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 neuroblastoma and Ramos BurkittAAasAasAas lymphoma lines.







