

HY-172350 · 50 mg
MedChemExpress · Cat: HY-172350
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Manufacturer product page
medchemexpress.com/wehi-p8.html
Description
WEHI-P8 is an orally active inhibitor targeting the papain-like protease PLpro of coronaviruses. WEHI-P8 againsts SARS-CoV-2 PLpro with an IC50 value of 12 nM. WEHI-P8 has good cellular activity with a EC50 of 298 nM. WEHI-P8 protects mice from SARS-CoV-2 induced long-term symptoms in lung and brain. WEHI-P8 can be used for post-acute sequelae of COVID-19 study.







