GENERAL CATALOGUE
WKYMVM-NH2
HY-P1121 · 50 mg
MedChemExpress · Cat: HY-P1121
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medchemexpress.com/wkymvm-nh2.htmlCatalog No: HY-P1121
CAS No: 187986-11-4
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
WKYMVM-NH2 is a hexapeptide that activates neutrophils and myeloid cells via the FPRL1 and FPRL2 receptors. It exhibits EC50 values of 2 nM and 80 nM in HL-60-FPRL1 and HL-60-FPRL2 cells, respectively. In HL-60 cells stably expressing FPRL2, WKYMVM-NH? induces chemotaxis, with optimal migration observed at concentrations ranging from 10 to 50 nM. It also stimulates superoxide production in neutrophils, with an EC50 of 75 nM. WKYMVM-NH? is a useful tool for research in the field of inflammatory diseases.
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