Wnt5a Rabbit Monoclonal Antibody

Description

EnkiLife offers the Wnt5a Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF application. Alternative Names of Immunogen: WNT5A; Protein Wnt-5a. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200 Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Research Area: Neuroscience