GENERAL CATALOGUE
WQQ-345
HY-169061 · 50 mg
MedChemExpress · Cat: HY-169061
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Manufacturer product page
medchemexpress.com/wqq-345.htmlCatalog No: HY-169061
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
WQQ-345 is a BCAT1 inhibitor with an IC50 value of 10.8 mM. WQQ-345 can lead to a decrease in ?-KG levels, an upregulation of H3K27me3 expression, a reduction in the expression of glycolytic enzymes PFKP and LDHA , and impaired glycolytic activity in 67R cells. WQQ-345 shows tumor-suppressing activity in a 67R subcutaneous xenograft model.
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