GENERAL CATALOGUE
WRR-483
HY-118338 · 50 mg
MedChemExpress · Cat: HY-118338
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medchemexpress.com/wrr-483.htmlCatalog No: HY-118338
CAS No: 1076088-50-0
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
WRR-483 is an analog of K11777, an inhibitor of cruzain, used to inhibit the proliferation of Trypanosoma cruzi in cell culture. WRR-483 can eradicate parasitic infection in an acute Chagas disease mouse model. WRR-483 is an irreversible cysteine protease inhibitor that shows pH-dependent high affinity and potent trypanocidal activity against cruzain and T. cruzi infection, and is expected to inhibit Chagas disease.
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