WT1 126-134 peptide

Description

WT1 126-134 peptide is a Wilms tumor oncogene protein WT1 peptide RMFPNAPYL . WT1 126-134 peptide is presented by HLA-A0201 and induces cytotoxic CD8 T cells capable of killing WT1+ positive tumor cells. WT1 126-134 can form stable complexes with the H-2Db mouse or HLA-A0201 human molecules. WT1 126-134 peptide/HLA-A0201 complex has an extremely high affinity Kd = 0.2 nM with the humanized monoclonal antibody IgG1 . WT1 126-134 peptide can be used as a vaccine for T cells or as a target for antibodies.