GENERAL CATALOGUE
WWL0245
HY-153519 · 50 mg
MedChemExpress · Cat: HY-153519
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Manufacturer product page
medchemexpress.com/wwl0245.htmlCatalog No: HY-153519
CAS No: 2869057-11-2
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
WWL0245 is a potent and seletive BRD4 PROTAC. WWL0245 selectively degrades BRD4 with sub-nanomolar DC50 1 nM than BRD2/3 and PLK1 DC50 1 ?M . WWL0245 shows excellent selective cytotoxicity in the BETi sensitive cancer cell lines, including AR-positive prostate cancer cell lines. WWL0245 is a promising drug candidate for AR-positive prostate cancer research and a valuable tool compound to study the biological function of BRD4.
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