GENERAL CATALOGUE
WWL123 analogue-1
HY-132246 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-132246
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medchemexpress.com/wwl123.htmlCatalog No: HY-132246
CAS No: 1338575-41-9
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
WWL123 analogue-1 is an analogue of WWL123. WWL123 is a potent and selective ABHD6 inhibitor with an IC50 of 430 nM. WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole PTZ -induced epileptiform seizures and spontaneous seizures in R6/2 mice.
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