GENERAL CATALOGUE
WZH-17-002
HY-174315 · 50 mg
MedChemExpress · Cat: HY-174315
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/wzh-17-002.htmlCatalog No: HY-174315
Category: MAPK ERK Pathway
Pack Size: 50 mg
Brand: MedChemExpress
Description
WZH-17-002 is a WZH-15-125-based ALK PROTAC degrader with a DC50 of 25 nM. WZH-17-002 enhances activities against Lorlatinib HY-12215 -resistant ALK compound mutations. WZH-17-002 significantly reduces drug resistance in ALK-fusion non-small cell lung cancer NSCLC and inhibits tumor growth in EML4-ALK G1202R/L1196 M xenograft mice model. Pink: ALK ligand HY-174314 ; Blue: CRBN ligase ligand HY-14658 ; Black: linker HY-174316
More from MedChemExpress
?-Glycerophosphate disodium salt pentahydrate
HY-D0886
MAPK ERK Pathway
D-87503
HY-108959
MAPK ERK Pathway
LC-SF-14
HY-172916
MAPK ERK Pathway
MCB-22-174
HY-165607S
MAPK ERK Pathway
MAP855
HY-145702
MAPK ERK Pathway
SHR2415
HY-151367
MAPK ERK Pathway
Cuspin-1
HY-119460
MAPK ERK Pathway
Loureirin B
HY-N1504
MAPK ERK Pathway