GENERAL CATALOGUE
XMU-MP-9
HY-162809 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-162809
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Manufacturer product page
medchemexpress.com/xmu-mp-9.htmlCatalog No: HY-162809
CAS No: 2251130-41-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used for the study of colon, lung and pancreatic cancer.
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