

HY-149085 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-149085
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medchemexpress.com/xs-060.htmlDescription
XS-060 is a potent anticancer agent and RXR? antagonist. XS-060 significantly induces RXR?-dependent mitotic arrest by inhibiting pRXR?-PLK1 interaction. XS-060 inhibits p-RXR? interaction with PLK1 but has no effect on RXR? heterodimerization with RAR?. XS-060 inhibits the in situ interaction between p-RXR? and PLK1 at the centrosome.







