GENERAL CATALOGUE
XY-52
HY-155193 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155193
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Manufacturer product page
medchemexpress.com/xy-52.htmlCatalog No: HY-155193
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
XY-52 Compound 32 is a Stimulation-2 ST2 inhibitor, with an IC50 value of 5.68 ?M in AlphaLISA assay, and 4.59 ?M in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFN? biomarkers in the graft versus host disease GVHD mice model.