Yamogenin

Description

Yamogenin Neodiosgenin is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor LXR in luciferase ligand assay. Yamogenin inhibits triacylglyceride TG accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC50 of 1421.92 ?g/mL. Yamogenin can be studied in research on gastric cancer.