GENERAL CATALOGUE
YC137
HY-123244 · 50 mg
MedChemExpress · Cat: HY-123244
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medchemexpress.com/yc137.htmlCatalog No: HY-123244
CAS No: 810659-53-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
YC137 is a potent Bcl-2 antagonist with Kis of 1.3 ?M and >100 ?M for Bcl-2 and Bcl-xL when assayed in Bis-Tris buffer, respectively. YC137 inhibits the binding of the Bid BH3 peptide to Bcl-2, thus disrupting an interaction essential for the antiapoptotic activity of Bcl-2. YC137 selectively induces apoptosis of Bcl-2-dependent cells. YC137 has the potential for breast cancer research.
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