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YCH1899
GENERAL CATALOGUE

YCH1899

HY-155993 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-155993

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medchemexpress.com/ych1899.html
Catalog No: HY-155993
CAS No: 3032451-66-1
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

YCH1899 is an orally active PARP inhibitor, with an IC50 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib HY-10162 -resistant and Talazoparib HY-16106 -resistant Capan-1 cells Capan-1/OP and Capan-1/TP cells , with IC50 values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats.

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