GENERAL CATALOGUE
Yck2-IN-1
HY-168998 · 50 mg
MedChemExpress · Cat: HY-168998
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medchemexpress.com/yck2-in-1.htmlCatalog No: HY-168998
CAS No: 401816-26-0
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Yck2-IN-1 Compound 2a is an inhibitor of the fungal Candida albicans Yck2 kinase. It exhibits an IC50 of approximately 80 nM against Yck2 and a MIC80 of 12.5 AAasAasAAmuM against C. albicans, with good metabolic stability 66 % remaining in mouse liver microsomes . In a mouse model of drug-resistant candidiasis, Yck2-IN-1 significantly reduced fungal burden in the kidneys. Yck2-IN-1 holds promise for research in the field of antifungal infection.
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