GENERAL CATALOGUE
YF135
HY-144323 · 50 mg
MedChemExpress · Cat: HY-144323
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/yf135.htmlCatalog No: HY-144323
CAS No: 2913177-53-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
YF135 is an efficient and reversible-covalent KRASG12C PROTAC. YF135 is designed and synthesized by tethering KRAS G12C inhibitor 48 compound 6d as the ligand, and basing on the scaffold of MRTX849 linkage VHL ligand. YF135 significantly induces the degradation of KRASG12C in a reversible manner and decreases phospho-ERK level through the E3 ligase VHL mediated proteasome pathway.
More from MedChemExpress
TP-061
HY-103041
Cell Cycle DNA Damage
Guttiferone G
HY-N9892
Cell Cycle DNA Damage
C
Cdk14 Mouse Pre-designed siRNA Set A
HY-RS02363
Cell Cycle DNA Damage
HSP70/SIRT2-IN-2
HY-149638
Cell Cycle DNA Damage
Tucidinostat (Standard)
HY-109015R
Cell Cycle DNA Damage
C
CDK2 Human Pre-designed siRNA Set A
HY-RS02374
Cell Cycle DNA Damage
Palmitic acid-d2-1
HY-N0830S11
Cell Cycle DNA Damage
Cdc7-IN-1
HY-101523
Cell Cycle DNA Damage