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YQ128
GENERAL CATALOGUE

YQ128

HY-130252 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-130252

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medchemexpress.com/yq128.html
Catalog No: HY-130252
CAS No: 2454246-18-3
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

YQ128 is a potent and selective second-generation NLRP3 NOD-like receptor P3 inflammasome inhibitor with an IC50 of 0.30 ?M. YQ128 significantly and selectively suppresses the production of IL-1?, but not TNF-?, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity. YQ128 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.

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