GENERAL CATALOGUE
Z21115
HY-161936 · 50 mg
MedChemExpress · Cat: HY-161936
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medchemexpress.com/z21115.html
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Catalog No: HY-161936
CAS No: 2958668-54-5
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
Z21115 is an orally active inhibitor for phosphodiesterase 4 PDE4 , that inhibits PDE4D7 with IC50 of 10.5 nM. Z21115 inhibits Lipopolysaccharide HY-D1056 -induced expression of IL-6, TNF-? and iNOS. Z21115 exhibits anti-inflammatory activity in DSS HY-116282 -induced mouse colitis models without significant toxicity 1 g/kg .
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