GENERAL CATALOGUE
Z218484536
HY-160955 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-160955
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medchemexpress.com/z218484536.htmlCatalog No: HY-160955
CAS No: 1223877-07-3
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Z218484536 is a selective and brain-penetrant phosphoserine phosphatase PSPH inhibitor. Z218484536 binds to PSPH with a Kd value of approximately 0.23 ?M. Z218484536 reduces L-serine and D-serine levels in astrocytes. Z218484536 is able to suppress spontaneous epileptic seizures without causing serious side effects. Z218484536 also shows good anti-epileptic effects in the temporal lobe epilepsy TLE model.
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