ZAP70 (4B2) Mouse Monoclonal Antibody

Description

EnkiLife offers the ZAP70 (4B2) Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IP application. Alternative Names of Immunogen: ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IP 1:20-1:50 Background: The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck. Research Area: Immunology