ZAP70 Rabbit Monoclonal Antibody

Description

EnkiLife offers the ZAP70 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,ICC/IF,FC,IP application. Alternative Names of Immunogen: SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:50 Background: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]