GENERAL CATALOGUE
Zaptuzumab
HY-P991570 · 1 mg
MedChemExpress · Cat: HY-P991570
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medchemexpress.com/zaptuzumab.html
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Catalog No: HY-P991570
CAS No: 2378046-35-4
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Zaptuzumab AD5-10 is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death ACD . Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models.
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