GENERAL CATALOGUE
Zelasudil
HY-148808 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-148808
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Catalog No: HY-148808
CAS No: 2365193-22-0
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Zelasudil RXC007 is an orally active, highly selective small molecule Rho-associated coiled-coil containing protein kinase 2 ROCK2 inhibitor with anti-fibrotic efficacy. Zelasudil elicits positive immunomodulatory effects in metastatic pancreatic tumors with increase of CD8+ and CD4+ T cell infiltrate into the tumor cortex and reduction in immunosuppressive FOXP3+ regulatory T cells at the tumor border. Zelasudil is promising for research of pancreatic ductal adenocarcinoma.
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