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ZG-126
GENERAL CATALOGUE

ZG-126

HY-161778 · 50 mg

MedChemExpress · Cat: HY-161778

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medchemexpress.com/zg-126.html
Catalog No: HY-161778
CAS No: 3049802-32-3
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

ZG-126 is an agonist for vitamin D receptor VDR and an inhibitor for histone deacetylase HDAC IC50=0.63-67.6 ?M . ZG-126 exhibits cytotoxicity in cancer cells MDA-MB-231 and 4T1. ZG-126 exhibits antitumor and anti-metastatic efficacy against melanoma and triple-negative breast cancer TNBC in mouse models. ZG-126 also exhibits anti-inflammatory activity, through the reduction of macrophage infiltration and immunosuppressive M2-polarization.

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