

HY-161778 · 50 mg
MedChemExpress · Cat: HY-161778
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medchemexpress.com/zg-126.htmlDescription
ZG-126 is an agonist for vitamin D receptor VDR and an inhibitor for histone deacetylase HDAC IC50=0.63-67.6 ?M . ZG-126 exhibits cytotoxicity in cancer cells MDA-MB-231 and 4T1. ZG-126 exhibits antitumor and anti-metastatic efficacy against melanoma and triple-negative breast cancer TNBC in mouse models. ZG-126 also exhibits anti-inflammatory activity, through the reduction of macrophage infiltration and immunosuppressive M2-polarization.





