GENERAL CATALOGUE
Zimberelimab
HY-P99109 · 1 mg
MedChemExpress · Cat: HY-P99109
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Catalog No: HY-P99109
CAS No: 2259860-24-5
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Zimberelimab GLS-010 is a fully human IgG4 anti-PD-1 monoclonal antibody with an EC50 of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC50 values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical HodgkinAAasAasAas lymphoma.
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