GENERAL CATALOGUE
ZINC110492
HY-Q51222 · 5 mg
MedChemExpress · Cat: HY-Q51222
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medchemexpress.com/6-3-nitrophenyl-5h-dibenzo-c-e-azepine-5-...Catalog No: HY-Q51222
CAS No: 100264-64-0
Pack Size: 5 mg
Brand: MedChemExpress
Description
ZINC110492 is a selective ligand of CS-?Ex4 a splicing isoform of citrate synthase CS . ZINC110492 does not bind to CS full-length CS-FL . ZINC110492 inhibits colorectal cancer CRC cell growth in cells overexpressing CS-?Ex4 with an IC50 of 7.840 AAasAasAAmuM. ZINC110492 significantly decreases both citrate and 2-hydroxyglutarate 2-HG levels in the CS-?Ex4-overexpressing SW1116 cells.
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