GENERAL CATALOGUE
(-)-ZK 216348
HY-123352A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-123352A
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medchemexpress.com/minus-zk-216348.htmlCatalog No: HY-123352A
Category: Immunology Inflammation
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
- -ZK 216348 is the enantiomer of + -ZK 216348 HY-123352 . + -ZK 216348 is a nonsteroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to Progesterone and mineralocorticoid receptors with IC50s of 20.4 nM and 79.9 nM, respectively. ZK 216348 has antiinflammatory activity similar to Prednisolone and induces less transactivation-mediated side effects.
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