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ZK53
GENERAL CATALOGUE

ZK53

HY-149677 · 5 mg

MedChemExpress · Cat: HY-149677

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medchemexpress.com/zk53.html
Catalog No: HY-149677
CAS No: 3031789-26-8
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress

Description

ZK53 is a selective activator of mitochondrial caseinolytic protease P HsClpP EC50: 1.37??M for ?-casein hydrolysis by HsClpP . ZK53 is is inactive toward bacterial ClpP proteins. ZK53 induces apoptosis in H1703, H520 and SK-MES-1 cells. ZK53 induces dysregulation of mitochondrial functions in lung squamous cell carcinoma LUSC cells. ZK53 inhibits tumor growth in H1703 xenograft mouse model.

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