GENERAL CATALOGUE
ZLDI-8
HY-123931 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-123931
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medchemexpress.com/zldi-8.htmlCatalog No: HY-123931
CAS No: 667880-38-8
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition EMT related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase Lyp inhibitor with an IC50 of 31.6 ?M and a Ki of 26.22 ?M. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 ?M.
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