GENERAL CATALOGUE
ZLMT-12
HY-151436 · 50 mg
MedChemExpress · Cat: HY-151436
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Catalog No: HY-151436
CAS No: 2841473-39-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
ZLMT-12 compound 35 , tacrine derivatives, is a potent, orally active CDK2/9 inhibitor with IC50 values of 0.002 and 0.011 ?M for CDK9 and CDK2, respectively. ZLMT-12 has a weak inhibitory effect on AChE IC50=19.023 ?M and BChE IC50=2.768 ?M . ZLMT-12 has low toxicity and antiproliferative activity. ZLMT-12 induces apoptosis and arrests the cell cycle in the S phase and G2/M phase.
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