

HY-133829 · 500 g
MedChemExpress · Cat: HY-133829
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medchemexpress.com/zofenoprilat.htmlDescription
Zofenoprilat is an orally active inhibitor for angiotensin converting enzyme ACE with an IC50 of 1.7 nM. Zofenoprilat inhibits the expression of angiotensin II, reduces the blood pressure, exhibits thus cardioprotective and renalprotective activity. Zofenoprilat promotes the NO production, decreases endothelin-1 ET-1 expression, exhibits protective effect on vascular endothelial function. Zofenoprilat regulates oxidative stress-related molecules, exhibits antioxidant activity.







