

HY-174308 · 50 mg
MedChemExpress · Cat: HY-174308
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medchemexpress.com/zsa-215.html
Description
ZSA-215 is a potent and orally active STING agonist with an EC50 of 3.3 ?M. ZSA-215 enhances STING signaling through promoting the phosphorylation of STING and interferon regulatory factor 3 IRF3 and secretion of IFN-?. ZSA-215 inhibits tumor regression and long-term survival of mice in MC38 colon cancer model. ZSA-215 can be used to the study of colon cancerr.