

HY-124727 · 5 mg
MedChemExpress · Cat: HY-124727
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medchemexpress.com/zt55.htmlDescription
ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 ?M. ZT55 inhibits the proliferation of JAK2V617F-expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia.







