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ZT55
GENERAL CATALOGUE

ZT55

HY-124727 · 5 mg

MedChemExpress · Cat: HY-124727

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medchemexpress.com/zt55.html
Catalog No: HY-124727
CAS No: 2138488-38-5
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 ?M. ZT55 inhibits the proliferation of JAK2V617F-expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia.

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