GENERAL CATALOGUE
ZX703
HY-157788 · 50 mg
MedChemExpress · Cat: HY-157788
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Manufacturer product page
medchemexpress.com/zx703.htmlCatalog No: HY-157788
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
ZX703 compound 5I is a PROTAC that significantly degrades GPX4 in a dose- and time-dependent manner through the ubiquitin-proteasome and autophagy-lysosome pathways DC50=0.315 AAasAasAAmuM . ZX703 induces ferroptosis by inducing Reactive Oxygen Species ROS accumulation in cells. ZX703 can be used for cancer research.
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