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ZYJ-34c
GENERAL CATALOGUE

ZYJ-34c

HY-139815 · 50 mg

MedChemExpress · Cat: HY-139815

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medchemexpress.com/zyj-34c.html
Catalog No: HY-139815
CAS No: 1314556-93-8
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

ZYJ-34c is an orally active and potent histone deacetylase inhibitor HDACi with IC50s of 0.056 ?M and 0.146 ?M for HDAC6 and HDAC8, respectively. ZYJ-34c causes G1 phase arrest in low concentration. ZYJ-34c has antiproliferative activities. ZYJ-34c exhibits antitumor potency in MDA-MB-231 and HCT116 xenograft models and possesses antimetastatic potential in a mouse hepatoma-22 H22 pulmonary metastasis model.

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